Table 2.

Stepwise linear regression showing factors significantly associated with the mean annual change in MMSE in patients with Parkinson’s disease.

	B	SE	p
Age at disease onset, years	− 0.030	0.005	< 0.001
APOE ε4 carrier	− 0.470	0.103	< 0.001
Depressive mood	− 0.258	0.088	0.004
H&Y score at study enrollment	− 0.301	0.080	< 0.001

H&Y Hoehn and Yahr; MMSE mini-mental state exam.