Fig. 2.

Propofol inhibits the proliferation, migration and invasion of ES-2 and OVCAR-3 cells by downregualting HOST2 expression. a mRNA levels of HOST2 overexpression in ES-2 cells were detected by real-time PCR. b mRNA levels of HOST2 overexpression in OVCAR-3 cells were detected by real-time PCR. c Effects of HOST2 overexpression on the inhibitory effect of 5 μg/ml propofol on the activity of ES-2 cells were detected by CCK-8. d Effects of HOST2 overexpression on the inhibitory effect of 5 μg/ml propofol on the activity of OVCAR-3 cells were detected by CCK-8. e Effects of HOST2 overexpression on the inhibitory effect of 5 μg/ml propofol on the migration and invasiveness of ES-2 cells were detected by Scratch wound-healing and Transwell assays. f Effects of HOST2 overexpression on the inhibitory effect of 5 μg/ml propofol on the migration and invasiveness of OVCAR-3 cells were detected by Scratch wound-healing and Transwell assays. *p < 0.05, **p < 0.01 and ***p < 0.001