Table 1.

Effect of different concentration of MitoQ in maturation media on mouse oocytes developmental competence, compared to in vivo-control, in vitro-control and sham groups.

	In vivo-control	In vitro-control	Sham	MitoQ (0.01 µM)	MitoQ (0.02 µM)	MitoQ (0.04 µM)
Maturation rate	----	71.14 ± 0.91	69.25 ± 1.38	89.01 ± 1.40 a	92.6 ± 0.92a	83.05 ± 0.91c
Matured (per initiated)	178	156	163	169	153	171
Fertilization rate (%)	92.1±1.90a	78.84 ± 1.54	77.91 ± 1.31	85.79 ± 2.20	90.19 ± 2.01a	80.7 ± 1.58
Cleavage rate (%)	88 ± 2.48 a	65.75 ± 2.49	63.75 ± 1.31	76.66 ± 1.75 cd	80.62 ± 1.67ad	68 ± 1.47
Blastulation (%)	83 ± 2.48 b	58 ± 2.16	57.25 ± 2.56	73.5 ± 2.62 cd	81.66 ± 1.85b	64 ± 3.02

Each experiment involved four replicates. Mean ± SEM

Each experiment involved four replicates. Mean ± SEM

^aP ≤ 0.01 versus in vitro-control and sham

^bP ≤ 0.01 versus in vitro-control, sham, 0.01 and 0.04 μM MitoQ

^cP ≤ 0.05 versus in vitro-control and sham

^dP ≤ 0.05 versus 0.04 μM MitoQ