TABLE 3.
ROC analysis for the diagnosis of AD and healthy controls
| Variable | AUC | p Value | 95% CI | Boundary value (pg/ml) | Sensitivity (%) | Specificity (%) | |
|---|---|---|---|---|---|---|---|
| Lower bound | Upper bound | ||||||
| GSDMD | .9998 | <.0001 | .9991 | 1.0000 | 3.12 | 92.87 | 98.98 |
| T‐Tau | .9652 | <.0001 | .9342 | .9962 | 469.87 | 80.23 | 91.66 |
| Tau181p | .9062 | <.0001 | .8233 | .9287 | 84.43 | 76.98 | 88.98 |
| Aβ1−42 | .9547 | <.0001 | .8763 | .9432 | 532.87 | 78.98 | 90.98 |
| GSDMD/T‐Tau | .8225 | <.0001 | .7873 | .8552 | 2.14 | 68.98 | 80.98 |
| GSDMD/Tau181p | .7677 | <.0001 | .7111 | .8334 | 2.14 | 69.43 | 82.76 |
| GSDMD/Aβ1−42 | .7982 | <.0001 | .7663 | .8985 | 3.11 | 72.88 | 85.77 |