Table 1.
List of candidate single nucleotide polymorphisms assessed for variation, information related to their location and function, and genotype frequencies in our Long‐Evans rat population
| Gene | Coordinate | Location | Consequence | Accession number | Genotype frequencies | |
|---|---|---|---|---|---|---|
| Dopamine‐Related | ||||||
| Dopamine Receptor 1 (Drd1) | chr17:11100256 | Upstream | Unknown | rs105271298 | 33T/T, 12T/A, 1 A/A | |
| Dopamine Receptor 2 (Drd2) | chr8:53736747 | Exon | Synonymous | N/A | No variation | |
| chr8:53742670 | Intron | Unknown | rs107017253 | 34 A/A, 12 A/G | ||
| Dopamine Transporter (Dat) | chr1:32354790 | Exon | Synonymous | N/A | 12 A/A, 26 A/G, 8 G/G *,** | |
| chr1:32362114 | Exon | Synonymous | rs13448119 | 13 G/G, 25 G/A, 8 A/A *,** | ||
| Estrogen‐Related | ||||||
| Estrogen Receptor Alpha (Esr1) | chr1:41325782 | Exon | Synonymous | N/A | 15 C/C, 31 C/T | |
| chr1:41590586 | Exon | Synonymous | N/A | 31 C/C, 5 C/T, 10 T/T | ||
| Estrogen Receptor Beta (Esr2) | chr6:99180312 | Exon | Synonymous | rs8170138 | 37 A/A, 9 A/G *,** | |
| chr6:99184395 | Exon | Synonymous | rs13448055 | 37 G/G, 9 G/A *,** | ||
| chr6:99204426 | Exon | Synonymous | rs106738562 | 37 C/C, 9 C/T *,** | ||
| Aromatase (Cyp19a1) | chr8:58755644 | Exon | Synonymous | N/A | 13 T/T, 21 T/C, 12 C/C | |
| chr8:58755702 | Exon | Missense | rs197770329 | No variation | ||
| Neuropeptide‐Related | ||||||
| Prolactin Receptor (Prlr) | chr2:60285990 | Exon | Synonymous | rs199216170 | No variation | |
| Arginine Vasopressin (Avp) | chr3:123118892 | Intron | Unknown | rs197835086 | No variation | |
| Arginine Vasopressin Receptor 1a (Avpr1a) | chr7:67341790 | Intron | Unknown | rs199089038 | No variation | |
| Oxytocin Receptor (Oxtr) | chr4:144398803 | Downstream | Unknown | N/A | 23 A/A, 23 G/G | |
*,**
SNPs are in linkage disequilibrium.