Table 1.
Examples of drugs repositioned to a new antimicrobial classification.
| Therapeutic | Original class | Repositioned class | Approval year |
|---|---|---|---|
| Amphotericin B | Antifungal | Antiparasitic | 1997 (Meyerhoff, 1999) |
| Doxycycline | Antibiotic | Antimalarial | Off-label (Tan et al., 2011) |
| Eflornithine | Antitumour | Antiparasitic | 1990 (Simarro et al., 2012) |
| Miltefosine | Antitumour | Antiparasitic | 2014 (Smorenburg et al., 2000) |
| Paromomycin | Antibiotic | Antiparasitic | 1994 (Ben Salah et al., 2013) |
| Zidovudine | Anticancer | Antiviral | 1987 (Yarchoan et al., 1986) |