Table 1.
Characteristics and minimum inhibitory concentrations of polymyxin-resistant K. pneumoniae (mg/L).
| ID | HOSPITAL | YEAR | SOURCE | ROOM | POL | CZA | CAZ | FEP | TZP | ETP | IMI | MEM | DOR | CIP | TGC |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UEB_1 | M1 | 2009 | BLOOD | HOSP | 4 | 4/4 | >32 | >64 | >64/4 | >32 | >32 | >32 | >16 | >2 | 4 |
| UEB_2 | C1 | 2010 | SKIN | ER | 8 | ≤1/4 | >32 | >64 | >64/4 | >32 | 32 | >32 | >16 | >2 | ≤0.5 |
| UEB_3 | C1 | 2010 | BLOOD | ICU | 8 | 4/4 | >32 | >64 | >128/4 | >32 | 32 | >32 | >16 | >2 | ≤0.5 |
| UEB_4 | C1 | 2010 | SKIN | ICU | >8 | 4/4 | >32 | >64 | >128/4 | >32 | >32 | >32 | >16 | >2 | 1 |
| UEB_5 | B1 | 2010 | OTHER | HOSP | 4 | ≤1/4 | >32 | 64 | >128/4 | 2 | 1 | 1 | 1 | >2 | ≤0.5 |
| UEB_6 | M1 | 2011 | GI | ICU | >8 | 2/4 | >32 | 16 | >128/4 | 16 | 4 | 4 | 4 | 1 | ≤0.5 |
| UEB_7 | M1 | 2011 | SECRETION | ICU | 8 | 4/4 | >32 | 16 | >128/4 | >32 | 16 | >32 | >16 | 1 | 1 |
| UEB_8 | M1 | 2011 | GI | ICU | >8 | 2/4 | >32 | >64 | >128/4 | >32 | 16 | 32 | >16 | 1 | 1 |
| UEB_9 | M1 | 2011 | GI | ICU | 8 | ≤1/4 | >32 | 16 | 128/4 | 2 | 1 | 1 | ≤0.5 | 1 | 1 |
| UEB_10 | C1 | 2011 | GI | ICU | >8 | ≤1/4 | >32 | 64 | >128/4 | 32 | 4 | 16 | 16 | >2 | 2 |
| UEB_11 | B2 | 2011 | BLOOD | ICU | >8 | 4/4 | >33 | >64 | >128/4 | >32 | >32 | >32 | >16 | >2 | 2 |
| UEB_12 | M2 | 2011 | RESP TRACT | ICU | >8 | 4/4 | >32 | >64 | >128/4 | >32 | >32 | >32 | >16 | >2 | 1 |
| UEB_13 | M2 | 2011 | BLOOD | ICU | >8 | 4/4 | >32 | 64 | >128/4 | >32 | >32 | >32 | >16 | >2 | ≤0.5 |
| UEB_14 | M2 | 2011 | GI | ICU | >8 | 2/4 | >32 | 64 | >128/4 | >32 | >32 | >32 | >16 | >2 | 1 |
| UEB_15 | M2 | 2012 | URINE | HOSP | >8 | 4/4 | >32 | 64 | >128/4 | >32 | >32 | >32 | >16 | >2 | 1 |
| UEB_16 | C1 | 2014 | BLOOD | HOSP | >8 | ≤1/4 | >32 | >64 | >128/4 | 32 | >32 | >32 | >16 | >2 | 4 |
| UEB_17 | H1 | 2015 | RESP TRACT | ICU | >8 | 2/4 | >32 | 64 | >128/4 | >32 | >32 | >32 | >16 | 1 | 2 |
| UEB_18 | N1 | 2017 | BLOOD | ER | >8 | ≤1/4 | >32 | 32 | >128/4 | 4 | 2 | 1 | 2 | ≤0.25 | 4 |
| UEB_19 | H1 | 2017 | URINE | HOSP | >8 | ≤1/4 | >32 | 64 | >128/4 | >32 | 32 | 32 | >16 | >2 | 4 |
| UEB_20 | I1 | 2017 | URINE | HOSP | >8 | ≤1/4 | >32 | >64 | >128/4 | 32 | 8 | 16 | 16 | 1 | 2 |
| UEB_21 | B3 | 2019 | RESP TRACT | HOSP | >8 | 4/4 | >32 | >64 | >128/4 | >32 | >32 | >32 | >16 | >2 | 1 |
| UEB_22 | B3 | 2019 | PERIT LIQ | HOSP | >8 | 2/4 | >32 | >64 | >128/4 | >32 | >32 | >32 | >16 | >2 | 1 |
| UEB_23 | B3 | 2019 | ASCIT LIQ | HOSP | >8 | 4/4 | >32 | >64 | >128/4 | >32 | >32 | >32 | >16 | >2 | 1 |
| UEB_24 | I1 | 2016 | RESP TRACT | HOSP | >8 | >64/4 | >32 | >64 | >128/4 | >32 | >32 | 32 | >16 | >2 | 2 |
POL: polymyxin, CZA: ceftazidime-avibactam, CAZ: ceftazidime, FEP: cefepime, TZP: piperacillin-tazobactam, ETP: ertapenem, IMI: imipenem, MEM: meropenem, DOR: doripenem, CIP: ciprofloxacin, and TGC: tygecicline. C1: Cali, M1: institution 1 Medellin, M2: institution 2 Medellin, B1: Institution 1 Bogotá, B2: institution 2 Bogotá, B3: institution 3 Bogotá, N1: Neiva, I1: Ibague, H1: Pasto. ICU: intensive care unit, ER: emergency room, and HOSP: hospitalization room. GI: gastrointestinal, SKIN: Skin and Soft Tissue, RESP TRACT: respiratory Tract, PERIT LIQU: peritoneal liquid, ASCITIC LIQ: ascitic liquid.