Table 6.
Summary statistics for interstitial distribution volume (VD) measured in tumor, tumor inner rim and outer normal edge.
| Statistical parameters | VD tumor (× 10−1) | VD inner edge (× 10−1) | VD outer edge (× 10−1) | Flux (× 10−3) | ||||
|---|---|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | Mean | SD | Mean | SD | |
| Test values | 1.98 | 0.66 | 1.90 | 0.75 | 1.00 | 0.37 | 1.87 | 1.18 |
| Retest values | 2.24 | 0.70 | 1.99 | 0.80 | 0.99 | 0.43 | 1.89 | 1.83 |
| Mean difference | 0.26 | 0.65 | 0.09 | 0.85 | −0.01 | 0.38 | 0.02 | 1.13 |
| Paired t-test: p-value | 0.14 | 0.48 | 0.86 | 0.72 | ||||
| Wilcoxon sign test: p-value | 0.15 | 0.25 | 0.76 | 0.97 | ||||
| 95% CI for mean difference | (−0.10, 0.62) | (−0.40, 0.58) | (−0.23, 0.20) | (−0.63, 0.67) | ||||
| Intra-class correlation coefficient | 0.54 | 0.41 | 0.56 | 0.73 | ||||
Values from the normal outer edge were lower than from those from tumor inner rim, suggesting a decrease in interstitial space or compression of the peritumoral normal tissue. Flux values indicate the outward flow of the contrast agent, contributing to peritumoral edema often observed in solid tumors. Other details are same as in for Table 1.