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. Author manuscript; available in PMC: 2021 May 11.
Published in final edited form as: ACS Biomater Sci Eng. 2020 Apr 17;6(5):2943–2955. doi: 10.1021/acsbiomaterials.0c00116

Figure 1. Polymer synthesis and screening strategy.

Figure 1.

(a) Synthesis scheme of acrylate-terminated poly(β-amino ester)s (PBAE) base polymer, (b) conventionally end-capped ePBAEs, (c) poly(ethylene glycol)-co-poly(β-amino ester)s (PEG-PBAEs), and (d) monomers used in the synthesis of a library of PBAE-based polymers. (e) Workflow diagram of ePBAE and PEG-PBAE screening process for identification of the most optimal PEG-PBAE NP formulation.