Table 2.
Genotype and allele frequencies of TNF-α 238 and 308 variants in RPL patient and control groups. Statistical significance was defined at the level of 5% (p < 0.05)
| Total | RPL group | Control group | X2 | p-value | |
|---|---|---|---|---|---|
| (N = 111) | (N = 62) | (N = 49) | |||
| TNF-α − 238/308, n (%) | 3.749 | 0.694 | |||
| GG/GG | 50 (45.05) | 25 (40.32) | 25 (51.02) | ||
| GG/GA | 39 (35.14) | 24 (38.71) | 15 (30.61) | ||
| GG/AA | 12 (10.81) | 6 (9.68) | 6 (12.24) | ||
| GA/GG | 2 (1.80) | 2 (3.23) | 0 (0) | ||
| GA/GA | 7 (6.31) | 4 (6.45) | 3 (6.12) | ||
| GA/AA | 1 (0.90) | 1 (1.61) | 0 (0) | ||
| Allele, n (%) | 0.621 | 0.431 | |||
| G | 362 (81.53) | 199 (80.24) | 163 (83.16) | ||
| A | 82 (18.47) | 49 (19.76) | 33 (16.84) |