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. 2021 Apr 9;100(14):e25233. doi: 10.1097/MD.0000000000025233

Table 2.

Expression levels of BALF GM and serum biomarkers in the different groups.

No IPA Possible IPA Probable/proven IPA
BALF GM (ODI) 0.25[0.178 0.368] 0.733[0.426 1.77] 2.66[0.548 4.104]
 ≥0.5 ODI 26 (12.56%) 64 (69.57%) 26 (75.47%)
 ≥1.0ODI 6 (2.9%) 37 (40.22%) 21 (61.76%)
Serum GM (ODI) 0.163[0.113 0.227] 0.2[0.119 0.34] 0.31[0.185 0.975]
 ≥0.5 ODI 10 (4.83%) 11 (11.96%) 15 (44%)
 ≥1.0 ODI 2 (0.96%) 6 (6.52%) 8 (2.35%)
Serum BDG
 >10 pg/ml 8 (3.86%) 4 (4.34%) 6 (17.64%)
 >20 pg/ml 5 (2.41%) 1 (1.08%) 6 (17.64%)
PCT (μg/L) 0.06[0.03 0.12] 0.10[0.04 0.56] 0.12[0.04 1.69]
CRP (mg/L) 20.17[4.63 63.36] 54.45[11.97 144.55] 73.92[40.03,169.72]

BALF = bronchoalveolar lavage fluid, BDG = 1,3-β-d-glucan, CRP = C-reactive protein, GM = galactomannan, IPA = invasive pulmonary aspergillosis, ODI = optical density index, PCT = procalcitonin.

The data of ODI, PCT, and CRP in different groups were not in accordance with normal distribution and were expressed by median and interquartile range.

The methodology of serum BDG used 10 pg/ml as the detection limit of a positive result, so serum BDG was not analyzed as a digital variable.