Table 2.
Expression levels of BALF GM and serum biomarkers in the different groups.
| No IPA | Possible IPA | Probable/proven IPA | |
| BALF GM (ODI) | 0.25[0.178 0.368] | 0.733[0.426 1.77] | 2.66[0.548 4.104] |
| ≥0.5 ODI | 26 (12.56%) | 64 (69.57%) | 26 (75.47%) |
| ≥1.0ODI | 6 (2.9%) | 37 (40.22%) | 21 (61.76%) |
| Serum GM (ODI) | 0.163[0.113 0.227] | 0.2[0.119 0.34] | 0.31[0.185 0.975] |
| ≥0.5 ODI | 10 (4.83%) | 11 (11.96%) | 15 (44%) |
| ≥1.0 ODI | 2 (0.96%) | 6 (6.52%) | 8 (2.35%) |
| Serum BDG∗ | |||
| >10 pg/ml | 8 (3.86%) | 4 (4.34%) | 6 (17.64%) |
| >20 pg/ml | 5 (2.41%) | 1 (1.08%) | 6 (17.64%) |
| PCT (μg/L) | 0.06[0.03 0.12] | 0.10[0.04 0.56] | 0.12[0.04 1.69] |
| CRP (mg/L) | 20.17[4.63 63.36] | 54.45[11.97 144.55] | 73.92[40.03,169.72] |
BALF = bronchoalveolar lavage fluid, BDG = 1,3-β-d-glucan, CRP = C-reactive protein, GM = galactomannan, IPA = invasive pulmonary aspergillosis, ODI = optical density index, PCT = procalcitonin.
The data of ODI, PCT, and CRP in different groups were not in accordance with normal distribution and were expressed by median and interquartile range.
The methodology of serum BDG used 10 pg/ml as the detection limit of a positive result, so serum BDG was not analyzed as a digital variable.