Table 2.
Univariate and multivariate analysis of postoperative AKI based on the “KDIGO” criteria.
| Univariate analysis | Multivariate analysis | |||||
| Patient characteristics | OR | 95%CI | P | OR | 95%CI | P |
| Sex | .452 | .136–1.503 | .195 | |||
| Age | 1.054 | 1.023–1.086 | .001 | .990 | .927–1.057 | .762 |
| Hypertension | 2.637 | 1.465–4.745 | .001 | 9.366 | 2.260–38.805 | .002∗ |
| Diabetes | 2.828 | 1.375–5.816 | .005 | .395 | .066–2.352 | .307 |
| Liver cirrhosis | 1.111 | .561–2.198 | .763 | |||
| Hb | .970 | .957–.984 | .001 | .974 | .946–1.002 | .067 |
| PLT | 1.006 | 1.001–1.010 | .007 | 1.025 | 1.005–1.045 | .012∗ |
| Neutrophil | 1.228 | 1.089–1.386 | .001 | .062 | .009–427 | .005∗ |
| Lymphocyte | .025 | .009–.069 | .001 | .001 | .001–001 | .001∗ |
| SII | 1.002 | 1.002–1.003 | .001 | .997 | .994–1.001 | .110 |
| WBC | 1.193 | 1.066–1.335 | .002 | 3.099 | 5.190–174.537 | .001∗ |
| Albumin | .969 | .913–1.028 | .291 | |||
| TB | 1.047 | 1.021–1.074 | .001 | .995 | .955–1.036 | .793 |
| GGT | 1.001 | 1.000–1.002 | .022 | 1.010 | 1.005–1.015 | .001∗ |
| ALT | .967 | .949–.985 | .001 | .928 | .895–962 | .001∗ |
| AST | .999 | .992–1.006 | .750 | |||
| Baseline Cr | 1.009 | .998–1.020 | .114 | |||
| BUN | 1.024 | .974–1.077 | .345 | |||
| AFP | 1.000 | 1.000–1.000 | .374 | |||
| HBV DNA, ≥2000/<2000 | 1.000 | 1.000–1.000 | .411 | |||
| CLIP score, 0–1/2–3 | 5.764 | 2.962–11.219 | .001 | 1.495 | .108–19.638 | .776 |
| CTP, A/B | 4.622 | 1.655–12.910 | .003 | 1.401 | .107–18.316 | .797 |
| Surgery type, major/minor | 3.246 | 1.788–5.893 | .001 | 31.585 | 5.654–176.435 | .001∗ |
| Tumor size | 1.103 | 1.044–1.165 | .001 | .855 | .734–997 | .045∗ |
| Ascites | 1.599 | .655–3.899 | .302 | |||
| Within Milan criteria | 2.676 | 1.460–4.905 | .001 | 2.146 | .242–19.040 | .493 |
| Resection, R0/R1 | 2.697 | 1.440–5.052 | .002 | .787 | .147–4.200 | .779 |
| Differentiation, I–II/III–IV | .613 | .311–1.207 | .157 | |||
| Microwave | 1.548 | .865–2.770 | .141 | |||
AFP = α-fetoprotein, AKI = acute kidney injury, ALT = alanine aminotransferase, AST = aspartate aminotransferase, BUN = blood urea nitrogen, CLIP = The Cancer of the Liver Italian Group Score, Cr = creatinine, CTP = Child-Turcotte-Pugh classification, GGT = γ-glutamyltransferase, Hb = hemoglobin, HBV DNA = serum HBV DNA levels, HBV = hepatitis B virus, KDIGO = Kidney Disease Improving Global Outcomes, PLT = platelet, SII = systemic immune-inflammation index, TB = total bilirubin, WBC = white blood cell.
∗
P values < .05 were considered statistically significant.