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. 2021 Apr 9;100(14):e25200. doi: 10.1097/MD.0000000000025200

Table 5.

Discriminatory power of biomarkers for disease activity by the ROC curves in IBD patients.

Biomarkers Cutoff value Youden index Sensitivity (%) Specificity (%) Positive predictive value (%) Negative predictive value (%) P-value AUC AUC 95% Cl
CAR 0.06 0.51 83.05 68.09 90.74 51.61 <0.001 0.829 0.763–0.896
hsCRP (mg/L) 2.14 0.51 82.32 68.75 90.85 50.77 <0.001 0.808 0.738–0.877
ALB (g/L) 39.50 0.44 68.89 75.00 91.18 39.13 <0.001 0.791 0.726–0.857
HGB (g/L) 120.50 0.47 59.34 87.76 94.74 36.75 <0.001 0.812 0.748–0.875
ESR (mm/h) 11.50 0.51 73.89 77.08 92.36 44.05 <0.001 0.811 0.746–0.875
PLT (×109/L) 246.50 0.47 67.40 79.17 92.42 39.18 <0.001 0.750 0.672–0.827
BMI (kg/m2) 23.26 0.32 80.90 51.06 86.22 41.38 <0.001 0.702 0.621–0.782

ALB = albumin, BMI = body mass index, CAR = high-sensitivity C-reactive protein/albumin ratio, ESR = erythrocyte sedimentation rate, HGB = hemoglobin, hsCRP = high sensitivity C reactive protein, IBD = inflammatory bowel disease, PLT = platelet, ROC = receiver operating characteristics.