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. 2021 Apr 9;100(14):e25200. doi: 10.1097/MD.0000000000025200

Table 7.

Discriminatory power of biomarkers for disease activity as calculated by the ROC curves in UC patients.

Cutoff value Youden index Sensitivity (%) Specificity (%) Positive predictive value (%) Negative predictive value (%) P-value AUC AUC 95%Cl
CAR 0.06 0.77 82.19 95.00 98.36 59.38 <0.001 0.918 0.860–0.977
hsCRP (mg/L) 2.14 0.77 82.19 95.24 98.36 60.61 <0.001 0.912 0.851–0.973
ALB (g/L) 39.50 0.58 68.49 90.00 96.15 43.90 <0.001 0.876 0.799–0.952
HGB (g/L) 136.50 0.56 84.93 71.43 91.18 57.69 <0.001 0.882 0.808–0.955
ESR (mm/h) 14.50 0.58 57.53 100.00 100.00 40.38 <0.001 0.872 0.799–0.946
PLT (×109/L) 241.50 0.62 81.94 80.00 93.65 55.17 <0.001 0.851 0.750–0.951
BMI (kg/m2) 22.00 0.38 66.20 71.43 88.68 38.46 0.005 0.701 0.578–0.823

ALB = albumin, BMI = body mass index, CAR = high-sensitivity C-reactive protein/albumin ratio, ESR = erythrocyte sedimentation rate, HGB = hemoglobin, hsCRP = high sensitivity C reactive protein, PLT = platelet, ROC = receiver operating characteristics, UC = ulcerative colitis.