Table 1.
Characteristics of donor/recipient pairs in the haploidentical setting.
| NK Alloreactivity £ |
|||||
|---|---|---|---|---|---|
| UPN | Disease ¶ | Donor | Donor CMV § Status | Yes/No (Type) |
Relevant KIR |
| LM004 | AML | Mother | positive | Yes (C1) | KIR2DL2/L3 |
| LR001 | AML | Sister | negative | Yes (C2) | KIR2DL1 |
| GM005 | AML | Mother | negative | Yes (C2) | KIR2DL1 |
| UT006 | ALL | Mother | positive | Yes (C2) | KIR2DL1 |
| CR008 | ALL | Mother | positive | Yes (C2) | KIR2DL1 |
| CM002 | ALL | Mother | positive | Yes (Bw4) | KIR3DL1 |
| SQ003 | ALL | Mother | positive | No | n.a. & |
| SC009 | ALL | Mother | positive | No | n.a. |
| AV010 | AML | Mother | positive | No | n.a. |
| CZ011 | ALL | Mother | positive | No | n.a. |
| BF007 | AML | Mother | negative | No | n.a. |
£ Presence of Natural Killer (NK)alloreactivity was assessed using the Killer-cells Immunoglobulin-like Receptors (KIR) KIR/KIR ligand mismatch in the graft-versus-host direction model. & Not applicable. ¶ Acute Myeloid Leukemia (AML), Acute Lymphoblastic Leukemia (ALL); § Cytomegalovirus (CMV).