EVs	extracellular vesicles
BALF	bronchoalveolar lavage fluid
MVs	microvesicles
ILVs	intraluminal vesicles
MVB	multivesicular body
MISEV	Minimum Information for the Study of Extracellular Vesicles
NTA	nanoparticle tracking analysis
EGFR	epidermal growth factor receptor
MSCs	mesenchymal stem cells
OVA	ovalbumin
DTT	dithiothreitol
UC	ultracentrifugation
SEC	size-exclusion chromatography
INF-γ	interferon-γ
HLA	human leukocyte antigen
MHC	major histocompatibility complex
CD9	cluster of differentiation 9
NRG1	neuregulin-1
IL-13	interleukin-13
PBMCs	peripheral blood mononuclear cells
TNF-α	tumor necrosis factor α
CCL2	C–C motif chemokine ligand 2
COPD	chronic pulmonary obstructive disease
MPs	microparticles
TLMPs	T lymphocyte MPs
BECs	human bronchial epithelial cells
MCP-1	monocyte chemoattractant protein 1
MMP-9	metalloproteinase 9
PMN	polymorphonuclear cells
NE	neutrophil elastase
Mac-1	macrophage-1
ECM	extracellular matrix
AM	alveolar macrophage
CF	cystic fibrosis
CFTR	cystic fibrosis transmembrane conductance regulator
RAGE	receptor for advanced glycation end-products
ERK	extracellular signal-regulated kinase
VCAM	vascular cell adhesion protein
EPCAM	epithelial cell adhesion molecule
LCN2	neutrophil gelatinase-associated lipocalin
SOD2	superoxide dismutase
GPX3	glutathione peroxidase 3
SNAP23	synaptosomal-associated protein 23
IgE	immunoglobulin E
NO	nitric oxide
ROS	reactive oxygen species
ICAM-1	intercellular adhesion molecule-1
ALI	acute lung injury
ARDS	acute respiratory distress syndrome
sPLA2-IIA	group II secretory phospholipase
PLA2G2A	phospholipase A2 group II gene
NLR	nod-like receptor
NLRP3	NLR family pyrin domain containing 3
BMDMs	bone-marrow-derived macrophages
LPS	lipopolysaccharide
TJP-1	tight junction protein
KC	keratinocyte chemoattractant
VILI	ventilation-induced lung injury
ROCK	Rho kinase
MerTK	tyrosine-protein kinase
NF-κB	nuclear factor kappa-light-chain-enhancer of activated B cells
ILD	interstitial lung diseases
BEAS-B2	human bronchial epithelial cell line
SCLC	small-cell lung carcinoma
NSCLC	non-small-cell lung carcinoma
NTHi	nontypeable Haemophilus influenzae
ECs	epithelial cells
SOC	suppressors of cytokine signaling
STAT3	signal transducer and activator of transcription 3
JAK	Janus kinase
MPMVECs	mouse pulmonary microvascular endothelial cells
INPP4A	inositol polyphosphate 4-phosphatase type I A
PI3K/Akt	phosphatidylinositol 3-kinase/serine/threonine protein kinase B
FEV1	lung function parameter
MIP2	macrophage inflammatory protein 2
ATIs	alveolar epithelial type-I cells
NGS	next-generation sequencing
IPF	idiopathic pulmonary fibrosis
TGF-β	transforming growth factor β
MAP3K7	mitogen-activated protein kinase kinase kinase 7
TAB3	TGF-β-activated kinase 1/MAP3K7 binding protein 3
CRX-II	chest X-ray stage II
VC	vital capacity
FVC	FEV1/forced vital capacity ratio
LeuMP	microparticles derived from leucocytes
SB	spontaneous breathing
VC	ventilated control
MS	mass spectroscopy
LC-MS	liquid chromatography MS
NADP	nicotinamide adenine dinucleotide phosphate
DNMT3B	DNA (cytosine-5)-methyltransferase 3β
EGFR-TKIs	epidermal growth factor receptor tyrosine kinase inhibitors
cfDNA	cell-free DNA
CTC	circulating tumor cells
PD-L1	programmed cell death ligand 1