Aβ	amyloid β
ADL	activities of daily living
AD	Alzheimer’s disease
APP	amyloid precursor protein
APOE	apolipoprotein E
BACE1	β-secretase
BBB	blood–brain barrier
CNS	central nervous system
CR	complement receptors
CX3CR1	chemokine receptor1
CX3CL1	chemokine ligand1
Drp1	dynamin-related protein1
FcRs	Fc receptors
GDP	gross domestic product
IFNγ	interferon gamma
IL	interleukin
KDHC	α-ketoglutarate dehydrogenase complex
LEARn	Latent Early- life Associated Regulation
MA-5	mitochonic acid 5
Mfn	mitofusion
MIP	macrophage inflammatory protein
MMP	mitochondrial membrane potential
mPTP	mitochondrial permeability transition pore
NF-κB	nuclear factor kappa B
NFTs	neurofibrillary tangles
NLRP3	NLR family pyrin domain, containing 3
NLR	nucleotide-binding domain leucine-rich repeat
NMDARs	N-methyl-D-aspartate receptors
Opa1	optic dominant atrophy1
OXPHOS	oxidative phosphorylation
PDHC	pyruvate dehydrogenase complex
PD	Parkinson disease
PHF	paired helical filament
p-tau	phospho tau
PSEN	presenilin
RAGE	receptor for advanced glycation end products
ROS	reactive oxygen species
SCARA-1	scavenger receptor A-1
SRs	scavenger receptors
TCA	tricarboxylic acid cycle
TLRs	toll-like receptors
TNF-α	tumor necrosis factor-α
TREM2	triggering receptor expressed in myeloid cells 2
WHO	World Health Organization