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. 2021 Mar 25;26(7):1836. doi: 10.3390/molecules26071836

Table 3.

Examples of alkaloids and source species with over one million total occurrences in the GBIF. A source species is only included if it is identified botanically with the species level in the DNP and data on the genus level and above are excluded. Therefore, these are examples of simple alkaloids surpassing 1 million total occurrences and do not account for all examples. Occurrences collected at genus level include those for species. Pharmacological study references of alkaloids are queried on the chemical abstract service (CAS).

Alkaloid Species Pharmacological Studies Using the Alkaloid Occurrences of the Species Total Occurrences (Species and Genus Level)
4-Hydroxy-1,1-dimethylpyrrolidinium-2-carboxylate/achillein Achillea millefolium L., Betonica officinalis L., Marrubium vulgare L., etc. 72 1,292,871 2,278,697
2,6-Benzoxazolediol; 6-Me-ether Coix lacryma L., Triticum aestivum L., Zea mays L., Secale cereale L., etc. 12 1,292,114 1,263,403
2,4-Undecadiene-8,10-diynoic acid; (2E,4E)-form, 2-Methylpropylamide Chrysanthemum frutescens L., Achillea macrophylla L., Achillea ptarmica L., etc. 2 1,032,568 1,360,771
8-Azabicyclo[3.2.1]octane-1,2,3,4-tetrol/calystegine Atropa belladonna L., Solanum tuberosum L., Solanum dulcamara L., etc. 160 1,018,893 2,129,193
2,4-Undecadiene-8,10-diynoic acid; (2E,4E)-form, 2,3-Didehydropiperidide Otanthus maritimus (L.) Hoffmanns. and Link, Achillea millefolium L. and Achillea ptarmica L. 8 1,016,004 1,310,187
Homostachydrine; (S)-form Medicago sativa L. and Achillea millefolium L. 54 1,003,339 2,303,110