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. 2021 Mar 31;22(7):3627. doi: 10.3390/ijms22073627

Figure 4.

Figure 4

Loss of periostin causes a decrease in muscle fiber number during repeated muscle regeneration. (a) Muscle weight 7 days after the induction of muscle regeneration. n = 4–10. (b) Muscle weight 7 days after repeated induction of muscle regeneration. n = 14. (c) CSA of regenerating muscle fiber after repeated muscle regeneration. n = 6. (d) The average of CSA. n = 6. (e) The number of muscle fibers after repeated muscle regeneration. n = 6. (f) Immunostaining of CD31 after repeated muscle regeneration. Bar: 75 μm. (g) The number of CD31-positive blood vessels. n = 3. (h) Muscle weight of 12-week-old mdx and mdx/periostin-null mice. n = 3–6. (i) Representative H&E staining of mdx and mdx/periostin-null mice. (j) Plasma CK levels in mdx and mdx/periostin-null mice. n = 3–6. * p < 0.05 and *** p < 0.001 by Student’s t-test. Error bars indicate SEM.