Table 6.

The prediction results compared with those of other methods on the independent test dataset.

Layer	Method	$\mathbf{Acc}$	$\mathbf{Sn}$	$\mathbf{Sp}$	$\mathbf{MCC}$
First Layer (Enhancer Identification)	iEnhancer-2L [19]	0.730	0.750	0.710	0.460
	EnhancerPred [21]	0.740	0.735	0.745	0.480
	iEnhancer-EL [22]	0.748	0.710	0.785	0.496
	iEnhancer-5Step [23]	0.790	0.820	0.760	0.580
	iEnhancer-CNN [25]	0.775	0.783	0.790	0.585
	iEnhancer-XG [26]	0.667	0.749	0.586	0.340
	iEnhancer-GAN [This Study]	0.784	0.811	0.758	0.567
Second Layer (Enhancer Strength Identification)	iEnhancer-2L [19]	0.605	0.470	0.740	0.218
	EnhancerPred [21]	0.550	0.450	0.650	0.102
	iEnhancer-EL [22]	0.610	0.540	0.680	0.222
	iEnhancer-5Step [23]	0.635	0.740	0.530	0.280
	iEnhancer-CNN [25]	0.750	0.653	0.761	0.323
	iEnhancer-XG [26]	0.667	0.749	0.586	0.340
	iEnhancer-GAN [This Study]	0.749	0.961	0.537	0.505