Overview of EV-TRACK adipose-related entries. Records for “adipose”, “adipose tissue” and “adipocyte” search terms on the EV-TRACK knowledge database were combined and analyzed. A total of 64 entries were retrieved by the 31 December 2020 (https://evtrack.org/) [45]. (a) Pie chart showing the relative proportion of isolation methods used. It should be noted that differential ultracentrifugation (dUC) was present in all entries; therefore, the rest of the methods reported were applied (if so) in combination. (b) Bar graph reflecting the number of entries reporting none, one, two, three, four, or more extracellular vesicle (EV) (blue) and non-EV (grey) markers. Pie charts reflect the relative proportion of EV (c) and non-EV (d) markers reported in the different studies (single or in combination with others).