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Atlas-based segmentation of the hippocampus involves the following sequential processes: (1) linear alignment of the Montreal Neurological Institute (MNI) brain atlas to the individual brain scans; (2) non-linear registration of the MNI atlas to the T1-weighted image; (3) warping the dilated binarized mask of the hippocampus to the patient space; and (4) cropping the region of interest.
