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. 2021 Mar 25;22(7):3396. doi: 10.3390/ijms22073396

Figure 1.

Figure 1

Expression of cyclooxygenase-1 (COX-1) in normal retina Photomicrographs of the retina in normal C57BL/6J mice. (a) The retinal section labeled with Iba1 (microglia/macrophage marker) and COX-1. There were COX-1+ cells in the GCL, IPL, INL, and OPL (white arrowheads). The COX-1 staining coincided with Iba1+ microglia (yellow arrowhead) that had ramified (resting state) morphology. Scale bar, 20 μm. (b) Photomicrographs showing a magnified image of microglia in the retina that had ramified morphology with long processes. Microglia with long processes were positive for Iba1 and COX-1. Scale bar, 10 μm. (c) The retinal section labeled with NeuN (neuronal marker) and COX-1. COX-1 staining did not coincide with NeuN+ cells. Scale bar, 20 μm. (d) The retinal section labeled with GFAP (astrocyte/Müller cell marker) and COX-1. COX-1 staining did not coincide with GFAP staining. Scale bar, 20 μm. (e) Retinal section labeled with Ly-6G (neutrophil marker) and COX-1. There were no Ly-6G+ cells in normal retina. Scale bar, 20 μm.