Table 1.
Group (n) | Baseline | Early Follow-Up | Late Follow-Up | ||
---|---|---|---|---|---|
Mean ± SD | Mean ± SD | p-Value vs. Baseline | Mean ± SD | p-Value vs. Baseline | |
Type of response | |||||
CR (29) | 6.1 ± 1.9 | 3.7 ± 2.3 | <0.0001 | 3.7 ± 2.9 | 0.0017 |
PR (17) | 6.3 ± 2.3 | 3.7 ± 2.0 | <0.0001 | 4.7 ± 2.2 | 0.0060 |
STD + PD (9) | 7.3 ± 0.9 | 6.9 ± 2.4 | 0.6235 | 7.4 ± 1.9 | 0.7882 |
Type of anatomical site of the Lesion(s) | |||||
A (11) | 6.0 ± 1.9 | 4.2 ± 2.1 | 0.0145 | 5.1 ± 2.4 | 0.2471 |
M (34) | 5.7 ± 2.1 | 3.8 ± 2.4 | <0.0001 | 4.1 ± 3.0 | 0.0051 |
P (10) | 8.2 ± 1.4 | 5.7 ± 2.9 | 0.0128 | 5.5 ± 2.2 | 0.0054 |
Number of lesion(s) | |||||
Single (34) | 5.8 ± 2.4 | 4.2 ± 2.5 | <0.0001 | 4.6 ± 2.9 | 0.0065 |
Multiple (21) | 6.8 ± 1.6 | 4.3 ± 2.5 | 0.0002 | 4.6 ± 2.6 | 0.0039 |
Size of lesion(s) | |||||
≤30 mm (37) | 5.7 ± 1.9 | 4.0 ± 2.5 | <0.0001 | 4.4 ± 2.9 | 0.0052 |
>30 mm (18) | 7.2 ± 2.2 | 4.8 ± 2.3 | 0.0002 | 5.1 ± 2.6 | 0.0070 |
Whole study population | |||||
55 | 6.1 ± 2.1 | 4.3 ± 2.5 | <0.0001 | 4.6 ± 2.8 | <0.0001 |
A, anterior; CR, complete response; M, intermediate; P, posterior; PD, progressive disease; PR, partial response; STD, stable disease.