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Binding pose between chemocoxib A and COX-2 (PDB ID: 4OTJ). The orange-colored surface represents the residues at the gate of COX activity. Since the binding pose was hidden by COX-2 residues, the upper figure is represented by removing residues from Thr71 to Lys83, and the lower figure was represented by removing residues from Tyr115 to Ser119.
