Table 4.

The closest distance between the kuwanon derivatives and amino acids in the entrance/exit routes of COX active sites.

Residues	Closest Distance (Å)
	Kuwanon A	Kuwanon B	Kuwanon C	Kuwanon E	Kuwanon H
Val89	2.595	2.195	1.404	1.961	2.142
His90	3.951	5.109	5.205	3.664	4.857
Ser119	6.440	7.132	6.301	7.665	3.778
Average	4.329	4.812	4.303	4.430	3.592