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. 2021 Mar 25;26(7):1856. doi: 10.3390/molecules26071856

Figure 4.

Figure 4

Cell cycle arrest is induced by co-treatment with 5-FU and CRE. The cell cycle distribution was analyzed in HCT116/R cells treated with CRE or 5-FU (A), and the relative percentages are indicated (B). Cell cycle-related protein expression levels (C) and the corresponding intensities were quantified (D). Data are expressed as the mean ± SD (n = 3) values. * p < 0.05 and ** p < 0.01, as compared to vehicle-treated cells. ## p < 0.01 compared to 5-FU-treated HCT116/R cells.