Aβ |
Amyloid-β |
AChE |
Acetylcholinesterase |
AD |
Alzheimer’s disease |
ADD |
AD with diabetes mellitus |
ADMET |
Absorption, distribution, metabolism, excretion, and toxicity |
AGEs |
Advanced glycation end products |
AOs |
Amine oxidases |
apoE |
Apolipoprotein E |
APP |
Amyloid precursor protein |
BACE-1 |
Beta-secretase 1 |
BBB |
Blood–brain barrier |
BuChE |
Butyrylcholinesterase |
CAA |
Cerebral amyloid angiopathy |
CAMs |
Cell adhesion molecules |
CNS |
Central nervous system |
DAO |
Diamine oxidase |
DM |
Diabetes mellitus |
DMBA |
7,12-dimethylbenz(alpha)anthracene |
EAE |
Experimental autoimmune encephalomyelitis |
ECE |
Endothelin-converting enzyme |
eMCAO |
Embolic MCAO |
FAD |
Flavin adenine dinucleotide |
FDA |
Food and Drug Administration |
GLUT |
Glucose transporters |
H2O2
|
Hydrogen peroxide |
HCHWA |
Hereditary cerebral hemorrhage with amyloidosis |
hCMEC/D3 |
Human cerebral microvascular endothelial cells |
HEVs |
High endothelial venules |
HIF-1 |
Hypoxia-inducible factor 1 |
HT |
Hemorrhagic transformation |
HUVEC |
Human umbilical vein endothelial cells |
ICAM-1 |
Intracellular adhesion molecule 1 |
ICH |
Intracerebral hemorrhage |
IDE |
Insulin-degrading enzyme |
IL-1β |
Interleukin 1 beta |
IL-6 |
Interleukin 6 |
IFN- γ |
Interferon- γ |
IRF1 |
Interferon regulatory factor 1 |
JL-72 |
3-(3-hydrazinylpropyl)-1H-indole |
JNK |
c-Jun amino-terminal kinase |
LOX |
Lysyl oxidase |
LPS |
Lipopolysaccharide |
LRP-1 |
Lipoprotein receptor protein-1 |
LTQ |
Lysine tyrosyl quinone |
MAO |
Monoamine oxidase |
MAPK |
Mitogen-activated protein kinase |
MCAO |
Middle cerebral artery occlusion |
MCI |
Mild cognitive impairment |
MMPs |
Matrix metalloproteinases |
MMSE |
Mini-mental state examination |
MS |
Multiple sclerosis |
MTDL |
Multi-target directed-ligand |
NEP |
Neprilysin |
NO |
Nitric oxide |
NOS |
Nitric oxide synthase |
NVU |
Neurovascular unit |
O2-
|
Superoxide |
OGD |
Oxygen–glucose deprivation |
OH· |
Hydroxyl radical |
PAO |
Polyamine oxidase |
PLN |
Peripheral lymph node |
PNAd |
Peripheral lymph addressin |
PrAO |
Primary amine oxidase |
PSEN |
Presenilin |
RAGE |
Receptor for advanced glycation end products |
ROS |
Reactive free radicals |
SAH |
Subarachnoid hemorrhage |
SAMP8 |
Senescence accelerated mouse-prone 8 |
SSAO |
Semicarbazide-sensitive amine oxidase |
STAT3 |
Signal transducer and activator of transcription 3 |
tMCAO |
Transient MCAO |
TNF-α |
Tumor necrosis factor α |
tPA |
Tissue plasminogen activator |
TPQ |
Topa-quinone |
VAP-1 |
Vascular adhesion protein-1 |
VCAM-1 |
Vascular cell adhesion protein 1 |
VEGF |
Vascular endothelial growth factor |