Table 4.
Alterations of SSAO/VAP-1 levels found in human ischemic stroke, intracerebral hemorrhage (ICH) and Alzheimer’s disease (AD).
| Disorder | Tissue Analyzed | Phase of the Pathology | SSAO/VAP-1 Alteration | Reference |
|---|---|---|---|---|
| Ischemic stroke | Serum | <6 h (acute phase) | Increase | [193] |
| Plasma | 24 h after stroke | Increase vs. 1 h | [92] | |
| Plasma | 1 h after HT | Increase | [92] | |
| Serum | >24 h after stroke | No change | [93] | |
| Plasma | weeks after | Decrease | [94] | |
| Ipsilateral brain | - | Decrease | [193] | |
| Ipsilateral brain | - | Increase | [92] | |
| Hemorrhagic stroke (ICH) | Plasma | 3–4 h after ICH | Increase | [95] |
| Contralateral brain | - | Increase | [95] | |
| AD | Plasma | moderate-severe | Increase | [97] |
| Plasma | - | Increase | [98] | |
| Brain vessels | - | Increase | [96] | |
| Hippocampus | - | Increase | [98] | |
| Brain vessels | - | Increase | [204] | |
| Brain vessels | - | Increase | [212] |