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. 2021 Mar 25;22(7):3369. doi: 10.3390/ijms22073369

Figure 9.

Figure 9

Proteomics analysis of storage EVs. (A) Heat map for proteins differing between βThal+ and control vesicles (n = 5 per group). (B) Representative boxplots showing statistically significant variation in the levels of specific EV proteins between the two groups. Light and dark colors indicate proteins of low and high abundance, respectively. (**) p < 0.05 and fold > 1.25 βThal+ vs. controls. Abbreviations: CCT6A: T-complex protein 1 subunit zeta; TAOK3: serine/threonine-protein kinase; YWHAE: 14-3-3 protein epsilon; PRKAR1A: cAMP-dependent protein kinase type I-alpha regulatory subunit; CAPNS1: calpain small subunit 1; PDCD6: programmed cell death protein 6; ART4: ecto-ADP-ribosyltransferase 4; IGA2: immunoglobulin alpha-2 heavy chain.