Table 2.
Intraoperative data and early postoperative complications.
| Variable | Tranexamic Acid n = 60 |
Control n = 61 |
p-Value |
|---|---|---|---|
| Intraoperative Data | |||
| Levels fused | 2 (1–3) | 2 (1–2) | 0.605 |
| Duration of anesthesia (min) | 240 ± 71 | 240 ± 68 | 0.996 |
| Duration of operation (min) | 186 ± 65 | 183 ± 63 | 0.819 |
| Crystalloids (mL) | 1475 (1050–1825) | 1400 (1050–1650) | 0.773 |
| Colloids (mL) | 250 (0–500) | 100 (0–500) | 0.716 |
| Urine output (ml) | 300 (150–535) | 260 (150–500) | 0.646 |
| Blood loss (mL) | 500 (300–800) | 500 (300–650) | 0.598 |
| Transfused red blood cell (mL) | 0 (0–0) | 0 (0–0) | 0.099 |
| Number of patient requiring vasopressor support * | 41 (68.3%) | 47 (77.0%) | 0.282 |
| Early postoperative complications | |||
| Hypotension requiring vasopressor support | 0 (0.0%) | 2 (3.3%) | 0.496 |
| Desaturation | 3 (5.0%) | 5 (8.2%) | 0.717 |
| Acute kidney injury | 0 (0.0%) | 3 (4.9%) | 0.244 |
| Total † | 3 (5.0%) | 8 (13.1%) | 0.121 |
Values are mean ± standard deviation, median (interquartile range), or the number of patients (percent). * Number of patients requiring ephedrine bolus more than two times (>8 mg) or phenylephrine/norepinephrine infusion; † total number of patients who developed one or more early postoperative complications.