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. 2021 Mar 24;22(7):3321. doi: 10.3390/ijms22073321

Table 2.

Practical Guidance for Heart-Protective Supplementation.

Nutraceutical Regimen Suggested for VH/HF Prevention
Multivitamin/mineral—Includes Mg, Zn, Cu, Se
Drink Powder—Spirulina, Citrulline, Taurine, Glycine, Soy Isoflavones, Cocoa Flavanols
Glutathione Booster Caps—N-Acetylcysteine, Lipoic Acid, Ferulic Acid
EPA/DHA Caps
Melatonin Cap
Nutraceuticals Which Could be Added for VH/HF Treatment
ER Stress Caps—Berberine, TUDCA
Ubiquinol
Carnitine
High-dose Folate
High-dose Biotin
Consider Also:
K Nitrate caps (or beet juice)
Mg Orotate
Astaxanthin

Ingredients chosen for the Drink Powder—excepting spirulina—are characterized by mild or absent flavor and high solubility. Once PhyCB becomes available in capsule form, this could be provided separately, such that spirulina would no longer need to be included in the Drink Powder. The “glutathione booster” product would be of particular value for the elderly, as Nrf2 activity and glutathione levels decline with increasing age.