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. 2021 Apr 1;13(7):1669. doi: 10.3390/cancers13071669

Table 3.

Summary of prehabilitation studies for pancreatic resection.

Year Study Design No. Exercise Plan Key Findings
Nakajima et al. 2019 Retrospective, cohort 76 30 days Unsupervised, self-reported exercise Shorter length of stay in prehabilitation group (23 days vs. 30 days, p = 0.045)
Ausania et al. 2019 Randomised controlled trial 18 2 weeks supervised and unsupervised, aerobic exercise Reduction in DGE in prehabilitation group (5.6% vs. 40.9%, p = 0.01)
Florez Bedoya et al. 2019 Prospective, cohort 23 15 weeks unsupervised, self-reported, aerobic and resistance exercise No comment on clinical outcomes
Evidence of prehabilitation increasing tumour vascularity.
Marker et al. 2018 Case series 3 12–16 weeks, supervised, physiotherapist reported, hour long, 3× a week Underpowered
Parker et al 2018 Prospective, cohort 50 60 min per week unsupervised, self-reported aerobic and strengthening exercise No comment on clinical outcomes
Home based exercise programme feasible
Ngo-Huang et al 2019 Prospective, cohort 50 2 weeks, unsupervised, self-reported, hour long aerobic exercise Prehabilitation associated with improved physical function (6MWT, STS, GS improved from baseline, p = 0.48, 0.03 & 0.08, respectively) and HRQOL (Improved with increased LPA (p = 0.01)

6MWT = 6 min walk test, STS = Sit to stand, GS = Gait speed, HRQOL = Health Related Quality of Life, LPA = Light physical activity.