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. 2021 Mar 29;13(7):1571. doi: 10.3390/cancers13071571
ADC antibody drug conjugate
ADCC antibody dependent cellular cytotoxicity,
ADCP antibody dependent cellular phagocytosis
APC antigen presenting cell
ASCT autologous stem cell transplantation
BCMA B cell maturation antigen
CDC complement dependent cytotoxicity
CR complete remission
d/D dexamethasone
Dara daratumumab
DIRA daratumumab specific immunofixation reflex assay
DM1 mertansine
DM4 ravtansine
EAT-2 Ewing’s sarcoma-associated transcript 2
Elo elotuzumab
EMA European Medicines Agency
FDA Food and Drug Administration
HR hazard ratio
IMiD immunomodulatory drug
IMWG International Myeloma Working Group
IRR infusion related reaction
Isa isatuximab
K carfilzomib
m month
MMAF monomethyl auristatin F
MoAb monoclonal antibody
MRD minimal residual disease
NDMM newly diagnosed multiple myeloma
NK natural killer
NR not reached
ORR overall response rate
P pomalidomide
PI proteasome inhibitor
PFS progression free survival
PN peripheral neuropathy
R lenalidomide
RBC red blood cell
RRMM relapsed/refractory multiple myeloma
SLAMF-7 Signaling Lymphocyte Activation Molecule Family 7
TE transplant eligible
TE transplant eligible
V bortezomib
VGPR very good partial remission