Figure 5.

Differential expression analysis in HUDEP2_L vs. CD34_L for known miRNAs. DEGseq highlights differences between primary cells and a prevalent cell model. (a) Differentially expressed (DE) known miRNAs in HUDEP2_L vs. CD34_L. Fold changes were plotted as the log₂ FC of miRNA expression in samples against the log₁₀ mean normalized miRNA counts calculated by differential expression analysis to aid legibility, only a selection of miRNAs of interest and DE miRNAs with high fold change or high levels of expression are labeled (see Table S8 for a full list). (b) The number of HUDEP2_L vs. CD34_L DE known miRNAs located in different chromosomes.