Table 1.

Gels applied to skin regeneration.

Authors	Materials	Process	Advantages	Disadvantages
You et al. [20]	NAg particles/CLG/CS	Freeze-drying	Bactericidal properties; Anti-inflammatory properties	Non-uniform morphology can damage fibroblast migration
Rubio-Elizalde et al. [21]	ALG/PEG–MA	Freeze-drying	Delayed degradation kinetics of ALG; Good antioxidant activity; Good antimicrobial activity; Good cell viability	Open pores on the surface can cause device contamination
Mahmoud et al. [62]	Norfloxacin/ CLG/CS	Freeze-drying	Good bio stability; Rapid release of norfloxacin	Polydisperse pores distribution
Anjum et al. [73]	CS/PEG/PVP/TC	Freeze-drying	No-scar formation	Burst effect during drug release
Zhu et al. [74]	Flu/ALG/CS	Freeze-drying + Amidation reaction	Good anti-inflammatory properties and good histocompatibility	Time-consuming process
Ramana Ramya et al. [78]	AGR/GLT/HAp	Freeze-drying + Gamma irradiation	Enhanced hemocompatibility; Enhanced antimicrobial activity and cell viability	Fast dissolution in aqueous medium
Franco et al. [80]	CAALG/MSG	SC-CO2 drying + SC-CO2 impregnation	Presence of a nanoporous structure; Structure suitable for cell attachment	Energy-consuming process
Valchuk et al. [81]	CS/ALG/ Levomycetin	SC-CO2 drying	Nanoporous structure	Burst effect during levomycetin release