Table 1.
Action potential parameters in atrial and ventricular myocytes from WT or Trpm4-/- animals. Data are represented as means ± SD. Note: #: p ≤ 0.05, WT vs. Trpm4−/−.
| Atrial | Ventricular | |||
|---|---|---|---|---|
| WT | Trpm4 −/− | WT | Trpm4 −/− | |
| RMP | −71.0 ± 3.6 | −68.9 ± 2.5 # | −81.1 ± 4.6 | −82.9 ± 5.1 |
| AMP | 107.0 ± 14.2 | 106.5 ± 12.3 | 112.0 ± 7.8 | 101.0 ± 11.5 |
| Vmax (mV/ms) | 107.7 ± 64.0 | 102.2 ± 48.0 | 115.8 ± 30.0 | 89.7 ± 28.3 # |
| APD 30 | 8.8 ± 4.3 | 9.0 ± 5.7 | 4.3 ± 3.2 | 4.7 ± 2.2 |
| APD 50 | 18.0 ± 8.7 | 18.5 ± 11.8 | 8.5 ± 6.0 | 8.6 ± 3.9 |
| APD 90 | 71.5 ± 19.7 | 77.8 ± 26.9 | 58.1 ± 30.3 | 52.7 ± 12.4 |