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. 2021 Mar 27;13(7):1548. doi: 10.3390/cancers13071548

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Fasn immunostaining in WT DEN and hSDC1^+/+ DEN livers. (a,b) A low amount of homogenously distributed cytoplasmic reaction was seen in hSDC1^+/+ DEN livers at month 3 and month 6. In WT livers, elevated immunostaining was detected in the preneoplastic foci at month 3 as well as in tumors at month 6. © At high magnification, intense cytoplasmic Fasn immunostaining was observed in the cytoplasm of cancer cells in WT DEN tumors. Representative image at 200× magnification, scale bar: 50 μm.