Table 5.
Differentially regulated proteins in WT DEN and hSDC1+/+ DEN at month 9.
| Gene Family | Family Members in WT DEN Group | Family Members in hSDC1+/+ DEN Group |
|---|---|---|
| Ribosome | ||
| Eif | 2a; 3g; 3i; 4g1; 4h | 3b; 3f; 4b |
| Rpl | 18a; 19; p1 | 13a; 27; 26; 28; 31; 34; 35a; 37a |
| Rps | - | 5; 24; 26 |
| Eef | - | 1a2 |
| Proteasome | ||
| Psm | c3; d4; d11; d14 | b5; b6; d12 |
| Numb | - | ✓ |
| Mitochondrial respiratory chain | ||
| Atp | - | 5d; 5c1; 6v1a |
| Cox | - | 7c |
| Nduf | - | b10; s4 |
| Mtch | - | 2 |
| mt-Nd | - | 5 |
| Myosin-actin | ||
| Myh | - | 1; 3; 4; 7; 8; 11; 14; |
| Myl | - | 1; 3; pf |
| Actn | - | 2; 3 |
| Tnn | - | c3 |
| Tpm | - | 2 |
| Des | - | ✓ |
| Atp | - | 2a1 |
| Fat net | ||
| Apo | a1; a4; c2; e; h | - |
| Pzp | ✓ | - |
| Serpin | a1b; a1c; c1; f2 | - |
| Calu | ✓ | - |
| Ahsg | ✓ | - |
| Anx | a1; a2 | - |
| Ola | 1 | - |
| Plg | ✓ | - |
| Mttp | ✓ | - |
| Clu | ✓ | - |
| Kng | 1 | - |
| mRNA splicing | ||
| Srsf | 1; 7 | - |
| Prp | 18 | - |
| Endoplasmic retic stress—protein folding | ||
| Dnaj | a2; b11; c3 | - |