Table 11.
Miscellaneous bioactivities of saponins isolated from Dracaena and Sansevieria species.
| Bioactivity | Saponin (Ref.) |
Description |
|---|---|---|
| Haemolytic effects | 152 [69] | No haemolytic effects and inhibition of the capillary permeability activity |
| Anti-inflammatory activity | 7 [51] | Anti-inflammatory activity on carrageenan-induced paw edema (maximum inhibitory activity of 71.22%) |
| 46 [51] | Anti-inflammatory activity on carrageenan-induced paw edema (maximum inhibitory activity of 80.57%) | |
| 97 [51] | Anti-inflammatory activity on carrageenan-induced paw edema (maximum inhibitory activity of 66.19%) | |
| Anti-neutrophilic inflammatory activity | 37 [58] | Inhibitory activity against formyl-L-methionyl-L-leucyl-L-phenylalanine-induced superoxide anion generation (IC50 = 18.55 ± 0.23 μM) and elastase release by human neutrophils (IC50 = 1.74 ± 0.25 μM) |
| 83 [58] | Inhibitory activity against formyl-L-methionyl-L-leucyl-L-phenylalanine-induced superoxide anion generation (IC50 = 26.39 ± 1.63 μM) and elastase release by human neutrophils (IC50 = 3.94 ± 0.19 μM) | |
| Antimicrobial activity | 25 [57] | Antimicrobial activities against Cryptococcus neoformans (MIC = 1 μg/mL) and Candida albicans (MIC = 2 μg/mL) |
| 28 [48] | Antifungal activity against Cryptococcus neoformans (IC50 = 20.0 μg/mL) | |
| 32 [62] | Antibacterial activity against Staphylococcus aureus | |
| 35 [48] | Antifungal activity against Cryptococcus neoformans (IC50 = 9.5 μg/mL) | |
| 57 [57] | Antimicrobial activities against Cryptococcus neoformans (MIC = 1–2 μg/mL) and Candida albicans (MIC = 2 μg/mL) | |
| 84 [57] | Antimicrobial activities against Cryptococcus neoformans (MIC = 1–2 μg/mL) | |
| 88 [57] | Antimicrobial activities against Cryptococcus neoformans (MIC = 1–2 μg/mL) and Candida albicans (MIC = 2 μg/mL) | |
| 91 [57] | Antimicrobial activities against Cryptococcus neoformans (MIC = 2 μg/mL) and Candida albicans (MIC = 4–8 μg/mL) | |
| Molluscicidal activity | 97 [66] | At the concentration of 5–6 ppm, spiroconazole A caused 100% mortality of the snails Bulinus globosus, B. forskalii, Biomphalaria pfeifferi, B. glabrata, and Lymnaea natalensis within 24 h. Other two related (unidentified) saponins were lethal with LC50 values in the range of 10–25 ppm |