Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Mar 25;13(7):1503. doi: 10.3390/cancers13071503

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

The protumor functions of C5a via M2 macrophages activation. (A) Correlation between plasma C5a and scavenger receptor (SA) expression level in the tumoral tissues. (B) cDNA expression array analysis of M1 and M2 macrophages treated with recombinant C5a compared to untreated group. (C) Expression of IL-17 in M2 macrophages after incubation of HCC-conditioned medium. (D) Double immunofluorescence image of a clinical tumoral section labeled with antibodies against IL-17 (green) and CD163 (red). (E) Expression of surface CD163 and intra-cellular IL-17 in total CD45+ population of tumoral, adjacent non-tumoral tissue and healthy liver tissue isolated from HCC patients measured by flow cytometry. Scale bar: 100 μm. Error bar indicated SEM. (Chi-square test for Figure 5A)(Unpaired t-test for Figure 5C).