Table 2.
Top 5 significantly enriched human gene atlas cell types and GTEx tissue samples in significantly upregulated CMs transcriptome.
Human Tissue/Cell Types | Overlap | p-Value | Adjusted p-Value |
---|---|---|---|
Human Gene Atlas (up-regulated genes in human tissues from BioGPS) | |||
Uterus | 94/405 | 5.11 × 10−13 | 2.15 × 10−11 |
Placenta | 58/201 | 1.17 × 10−13 | 9.85 × 10−12 |
Heart | 88/415 | 1.23 × 10−10 | 3.43 × 10−9 |
Smooth Muscle | 78/363 | 7.28 × 10−10 | 1.53 × 10−8 |
Cardiac Myocytes | 62/273 | 4.36 × 10−9 | 7.33 × 10−8 |
GTEx Tissue Samples (up-regulated genes) | |||
GTEX-X4EP-0326-SM-3P5Z6 heart female 60–69 years | 210/755 | 1.37 × 10−41 | 4.00 × 10−38 |
GTEX-X62O-0826-SM-46MW8 heart male 50–59 years | 208/766 | 1.79 × 10−39 | 2.62 × 10−36 |
GTEX-SE5C-0626-SM-2XCDV heart female 40–49 years | 229/906 | 4.75 × 10−38 | 4.62 × 10−35 |
GTEX-S3XE-0426-SM-3K2AC heart male 50–59 years | 163/547 | 2.78 × 10−36 | 2.03 × 10−33 |
GTEX-WY7C-1126-SM-3NB3A heart male 50–59 years | 176/637 | 1.88 × 10−34 | 1.09 × 10−31 |