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. 2021 Mar 24;22(7):3311. doi: 10.3390/ijms22073311

Table 2.

Top 5 significantly enriched human gene atlas cell types and GTEx tissue samples in significantly upregulated CMs transcriptome.

Human Tissue/Cell Types Overlap p-Value Adjusted p-Value
Human Gene Atlas (up-regulated genes in human tissues from BioGPS)
Uterus 94/405 5.11 × 10−13 2.15 × 10−11
Placenta 58/201 1.17 × 10−13 9.85 × 10−12
Heart 88/415 1.23 × 10−10 3.43 × 10−9
Smooth Muscle 78/363 7.28 × 10−10 1.53 × 10−8
Cardiac Myocytes 62/273 4.36 × 10−9 7.33 × 10−8
GTEx Tissue Samples (up-regulated genes)
GTEX-X4EP-0326-SM-3P5Z6 heart female 60–69 years 210/755 1.37 × 10−41 4.00 × 10−38
GTEX-X62O-0826-SM-46MW8 heart male 50–59 years 208/766 1.79 × 10−39 2.62 × 10−36
GTEX-SE5C-0626-SM-2XCDV heart female 40–49 years 229/906 4.75 × 10−38 4.62 × 10−35
GTEX-S3XE-0426-SM-3K2AC heart male 50–59 years 163/547 2.78 × 10−36 2.03 × 10−33
GTEX-WY7C-1126-SM-3NB3A heart male 50–59 years 176/637 1.88 × 10−34 1.09 × 10−31

Note: Enrichment analysis into human gene atlas and Genotype-Tissue Expression (GTEx) project tissue sample gene sets were performed in Enrichr [23,24], and gene sets were accessed on November 2020.