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. 2021 Mar 29;26(7):1919. doi: 10.3390/molecules26071919

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Photomicrographs of skin at day seven after wounding: (A) uninfected and untreated wounded skin showing a wide scab (SC) and scattered inflammatory cells in the dermis (D); (B) infected and untreated wounded skin revealing a scab (SC) interspersed with hemorrhage and granuloma (arrows); (C) infected and wounded skin treated with ZnO-NPs displaying a thin layer of scab with a wound edge (blue arrow) under which was a wide dermis area filled with inflammation (black arrow); (D) infected and wounded skin treated with imipenem exhibiting a scab (SC) interspersed with granuloma (arrow) and wide dermis (D) area filled with inflammatory cells (HE: 200×).