Table 2.
Effect of CPE on selected biochemical parameters of carbohydrate and lipid metabolism as well as general kidney function in rats.
| Parameters | ND | ND + CPE | DM | DM + CPE | DM + Met | DM + CPE + Met |
|---|---|---|---|---|---|---|
| Plasma Glucose (mg/dL) | 133.25 ±3.14 | 132.71 ± 2.61 | 428.47 ± 37.27 * | 237.45 ± 19.76 *,# | 218.43 ± 28.06 *,# | 231.10 ± 28.70 *,# |
| Plasma Triglycerides (mg/dL) |
42.43 ± 4.41 | 42.23 ± 5.93 | 80.12 ± 7.93 * | 43.82 ± 6.92 # | 50.69 ± 4.43 # | 40.73 ± 5.08 # |
| Plasma insulin (ng/mL) | 2.33 ± 0.35 | 2.81 ± 0.96 | 2.66 ± 0.50 | 1.89 ± 0.41 | 1.82 ± 0.35 | 1.97 ± 0.29 |
| HOMA Index | 20.13 ± 3.19 | 23.21 ± 7.97 | 72.19 ± 14.42 * | 29.05 ± 6.94 # | 26.54 ± 5.35 # | 26.14 ± 5.46 # |
| Estimated GFR (mL/min) | 1.30 ± 0.60 | 1.12 ± 0.34 | 1.30 ± 0.27 | 1.31 ± 0.18 | 1.37 ± 0.25 | 1.26 ± 0.45 |
HOMA index, homeostasis assessment of insulin resistance index; eGFR, estimated glomerular filtration rate. Each value is expressed as mean ± S.E.M (n = 6–8). * p < 0.05 indicates significant differences from normal (ND), and # p < 0.05 indicates significant differences from diabetes (DM).