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. 2021 Mar 31;13(7):1601. doi: 10.3390/cancers13071601
aCT adjuvant chemotherapy
aCRT adjuvant chemoradiotherapy
aRT adjuvant radiotherapy
AUC area under the blood concentration-time curve
Carbo Carboplatin
CDDP = cis Cisplatin
CI Confidence interval
DSS Disease-specific survival
EORTC European Organization for Research and Treatment of Cancer
5-FU 5-fluorouracil
HFX hyerfractionation
HR hazard ratio
KM Kaplan-Meier
LC local control
LP larynx preservation
LFS laryngectomy-free survival
n.a. not available
NCDB National Cancer Data Base
n pts. number of patients
OPL open partial laryngectomy
OR odds ratio
OS overall survival
PCM pharyngeal constrictor muscles
pCRT primary chemoradiotherapy
p(C)RT primary radiotherapy or primary chemoradiotherapy
pRT primary radiotherapy
SFX standard fractionation
surg +/- a(C)RT surgery with or without adjuvant (chemo)radiotherapy
TLM transoral laser microsurgery
TL total laryngectomy
TNM staging according to T = primary tumor, n = lymphnode metastases, and M = distant metastases
rTNM TNM of recurrent tumors
UICC Union International Contre le Cancer (International Union against Cancer
VA = VALCSG The Veterans Affairs Laryngeal Cancer Study Group