Table 1.
Demographic and clinical characteristics of 757 laryngeal cancer patients.
| Variable | Category | TLM | OPL | TL | pCRT | pRT | Total |
|---|---|---|---|---|---|---|---|
| Total | - | 443 | 59 | 172 | 38 | 45 | 757 |
| Age (cont) a | - | 62.5 (37–91) | 62.1 (34–84) | 61.9 (40–83) | 61.4 (41–81) | 64.9 (40–85) | 62.4 (34–91) |
| Sex | Males | 402 (90.7) | 57 (96.6) | 158 (91.9) | 32 (84.2) | 36 (80.0) | 685 (90.5) |
| - | Females | 41 (9.3) | 2 (3.4) | 14 (8.1) | 6 (15.8) | 9 (20.0) | 72 (9.5) |
| CCI | 0 | 331 (74.7) | 45 (76.3) | 114 (66.3) | 31 (81.6) | 22 (48.9) | 543 (71.7) |
| - | 1 | 112 (25.3) | 14 (23.7) | 58 (33.7) | 7 (18.4) | 23 (51.1) | 214 (28.3) |
| Localization | Glottic | 336 (75.8) | 49 (83.1) | 49 (28.5) | 8 (21.1) | 23 (51.1) | 465 (61.4) |
| - | Supraglottic | 96 (21.7) | 7 (11.9) | 57 (33.1) | 20 (52.6) | 14 (31.1) | 194 (25.6) |
| - | Subglottic | 4 (0.9) | 0 (0.0) | 8 (4.7) | 1 (2.6) | 1 (2.2) | 14 (1.8) |
| - | Transglottic | 4 (0.9) | 0 (0.0) | 38 (22.1) | 6 (15.8) | 3 (6.7) | 51 (6.7) |
| - | Unknown | 3 (0.7) | 3 (5.1) | 20 (11.6) | 3 (7.9) | 4 (8.9) | 33 (4.4) |
| T-Stage | 1 | 277 (62.5) | 32 (54.2) | 5 (2.9) | 5 (13.2) | 12 (26.7) | 331 (43.7) |
| - | 2 | 122 (27.5) | 17 (28.8) | 34 (19.8) | 9 (23.7) | 18 (40.0) | 200 (26.4) |
| - | 3 | 31 (7.0) | 7 (11.9) | 65 (37.8) | 11 (28.9) | 7 (15.6) | 121 (16.0) |
| - | 4 | 13 (2.9) | 3 (5.1) | 68 (39.5) | 13 (34.2) | 8 (17.8) | 105 (13.9) |
| n-Stage | 0 | 363 (81.9) | 54 (91.5) | 105 (61.0) | 19 (50.0) | 30 (66.7) | 571 (75.4) |
| - | 1 | 18 (4.1) | 0 (0.0) | 21 (12.2) | 3 (7.9) | 4 (8.9) | 46 (6.1) |
| - | 2 | 31 (7.0) | 2 (3.4) | 41 (23.8) | 11 (28.9) | 8 (17.8) | 93 (12.3) |
| - | 3 | 1 (0.2) | 0 (0.0) | 1 (0.6) | 3 (7.9) | 2 (4.4) | 7 (0.9) |
| - | X | 30 (6.8) | 3 (5.1) | 4 (2.3) | 2 (5.3) | 1 (2.2) | 40 (5.3) |
| UICC stage | I | 265 (59.8) | 31 (52.5) | 3 (1.7) | 3 (7.9) | 10 (22.2) | 312 (41.2) |
| - | II | 98 (22.1) | 17 (28.8) | 25 (14.5) | 6 (15.8) | 15 (33.3) | 161 (21.3) |
| - | III | 39 (8.8) | 6 (10.2) | 57 (33.1) | 10 (26.3) | 6 (13.3) | 118 (15.6) |
| - | IV | 41 (9.3) | 5 (8.5) | 87 (50.6) | 19 (50.0) | 14 (31.1) | 166 (21.9) |
| Adj. treat. | None * | 360 (81.3) | 52 (88.1) | 93 (54.1) | 38 (100) | 45 (100) | 588 (77.7) |
| - | aRT | 74 (16.7) | 7 (11.9) | 62 (36.0) | 0 (0.0) | 0 (0.0) | 143 (18.9) |
| - | aCRT | 5 (1.1) | 0 (0.0) | 17 (9.9) | 0 (0.0) | 0 (0.0) | 22 (2.9) |
| - | aCT | 4 (0.9) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 4 (0.5) |
TLM: transoral laser microsurgery, OPL: open partial laryngectomy, TL: total laryngectomy, pCRT: primary chemoradiotherapy, pRT: primary radiotherapy, CCI: Charlson Comorbidity Index, a Age (cont): age (continuous) in years: mean with minimal and maximal ages, Localization: primary tumor localization; Adj. treat.: adjuvant treatment; * in some charts the entry was missing, i.e., no adjuvant treatment or unknown status, aRT: adjuvant radiotherapy, aCRT: adjuvant chemoradiotherapy, aCR: adjuvant chemotherapy.