Table 4.
Survival and larynx preservation after TLM in T1, T2 and T1 + T2 laryngeal cancer patients of all primary tumor sites.
| Variable | T Category | Patients n (%) |
5-Year [%] (95%-CI) |
10-Year [%] (95%-CI) |
|---|---|---|---|---|
| DSS | T1 | 270 * (62.6) | 96 (92–98) | 93 (89–96) |
| - | T2 | 122 * (28.3) | 85 (77–90) | 78 (68–84) |
| - | T1 + T2 | 392 * (91.0) | 92 (89–95) | 88 (84–91) |
| OS | T1 | 277 (62.5) | 80 (75–84) | 58 (52–63) |
| - | T2 | 122 (27.5) | 73 (64–80) | 50 (41–59) |
| - | T1 + T2 | 399 (90.1) | 78 (73–82) | 55 (50–60) |
| LP | T1 | 277 (62.5) | 93 (89–96) | 93 (89–96) |
| - | T2 | 122 (27.5) | 82 (73–88) | 82 (73–88) |
| - | T1 + T2 | 399 (90.1) | 90 (86–93) | 90 (86–92) |
| LFS | T1 | 277 (62.5) | 74 (68–79) | 54 (48–60) |
| - | T2 | 122 (27.5) | 65 (56–73) | 46 (36–54) |
| - | T1 + 2 | 399 (90.1) | 71 (67–76) | 52 (47.57) |
DSS: disease-specific survival, OS: overall survival, LP: larynx preservation: event defined as occurrence of total laryngectomy, LFS: laryngectomy-free survival: OS with functional larynx, event defined as occurrence of either laryngectomy or death. * Differences in numbers of patients between OS and DSS due to unknown causes of death.