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. 2021 Mar 30;13(7):1102. doi: 10.3390/polym13071102

Table 1.

A list of the polymers mainly employed to prepare therapeutic Contact Lenses (CLs). pHEMA: poly (2-hydroxyethyl methacrylate); PMMA: poly (methyl methacrylate).

Polymer Properties
pHEMA
  • Biocompatible, but not biodegradable

  • Hydrophilic properties, due to the presence of an –OH group

  • Water-absorbing material

  • When dry, it has the properties of hard organic glass; after the hydration, it becomes soft and flexible

  • Generally display very poor mechanical properties

  • Generally employed for soft CLs, which are fragile/less durable but very comfortable

PMMA
  • Rigid/poorly flexible

  • High stability to UV and atmospheric agents

  • Limited chemical and heat resistance

  • Scarce permeability to oxygen

  • Excellent light transmission

  • Good mechanical and optical properties (e.g., transparency)

  • Low water-absorbing capacity

  • Generally used for rigid CLs, which are cheap and durable, but uncomfortable

Silicone/siloxane
  • Biocompatible, but not biodegradable

  • Chemical inert (e.g., not readily attracked by oxygen)

  • Resistance to water and oxidation

  • Highly flexible

  • Stability at both high and low temperatures

  • Very high permeability to gases

  • Generally employed for soft CLs, which are fragile/less durable but very comfortable