Figure 5.

400× magnified hematoxylin and eosin-stained sections. (A) 39 mm microscopic invasive ductal carcinoma corresponding to the one shown in Figure 3. The anatomopathological section shows moderately pleomorphic cells with a majority exhibiting irregular and oval shape. (B) Benign breast parenchyma adjacent to the tumor in Figure 5A. In contrast to the large, irregular nuclei in the tumor cells, the nuclei in the cells forming the benign mammary acini are round and uniformly smooth. Mean diffusion tensor size (E[D_iso]) value in this cancer was 1.09 × 10⁻³ mm²/s, compared to 2.32 × 10⁻³ mm²/s for the healthy glandular tissue, reflecting a higher cell density within the neoplastic section. Mean diffusion tensor shape (E[D_∆²]) value in this carcinoma was 0.64, compared to 0.26 for the healthy glandular tissue, which denotes predominantly elongated components within the cancerous tissue section.