Table 1.
Baseline characteristics stratified by low and high omega-3 fatty acid index groups
| Low Omega-3 Fatty Acid Index (n = 15) | High Omega-3 Fatty Acid Index (n = 16) | P value | |
|---|---|---|---|
| Omega-3 fatty acid index, median (IQR) | 2.4% [2.3,2.7] | 8.4% [8.1, 9.6] | <0.001 |
| Characteristic, n (%) | |||
| Age, mean (SD) | 63.1 (5.4) | 62.8 (8.2) | 0.90 |
| Female sex | 1 (6.7) | 6 (37.5) | 0.04 |
| History of myocardial infarction | 6 (40.0) | 7 (43.8) | 0.83 |
| History of PCI | 8 (53.3) | 8 (50.0) | 0.85 |
| History of CABG | 3 (20.0) | 4 (25.0) | 0.74 |
| Hypertension | 12 (80.0) | 8 (50.0) | 0.08 |
| Diabetes | 0 (0.0) | 0 (0.0) | NA |
| Anthropometrics and Blood Pressure, mean (SD) | |||
| Weight, kg | 89.3 (13.6) | 92.7 (14.3) | 0.51 |
| Body-mass index, kg/m2 | 30.5 (2.7) | 31.6 (3.3) | 0.37 |
| Waist circumference, cm | 106.4 (7.7) | 108.7 (11.5) | 0.51 |
| Blood pressure, mm Hg | |||
| Systolic | 125.6 (16.1) | 115.3 (14.3) | 0.07 |
| Diastolic | 74.2 (9.9) | 72.7 (11.8) | 0.71 |
| Biochemical Profile, mean (SD), except hs-CRP which is median [interquartile range] | |||
| Glycated hemoglobin, % | 5.8 (0.3) | 5.8 (0.4) | 0.67 |
| Glucose, mmol/L mg/dl | 5.22 (0.49) | 5.14 (0.61) | 0.69 |
| 94.0 (8.9) | 92.6 (11.0) | ||
| hs-CRP, nmol/L mg/L | 21.9 [1.9, 39.1] | 7.6 [3.8, 24.8] | 0.98 |
| 2.3 [0.2,4.1] | 0.8 [0.4,2.6] | ||
| Lipid profile, mean (SD) except triglyceride which is median [interquartile range] | |||
| Total cholesterol, mmol/L mg/dL | 4.00 (0.80) | 4.29 (1.06) | 0.41 |
| 154.5 (30.7) | 165.6 (40.8) | ||
| Triglyceride, mmol/L mg/dL | 1.41 [0.80,2.12] | 1.39 [0.98,2.06] | 0.74 |
| 125.0 [71.0,188.0] | 123.0 [87.0,182.0] | ||
| HDL-C, mmol/L mg/dL | 1.20 (0.32) | 1.32 (0.32) | 0.30 |
| 46.3 (12.3) | 51.1 (12.2) | ||
| LDL-C, mmol/L mg/dL | 80.1 (23.2) | 87.3 (34.5) | 0.51 |
| 2.07 (0.60) | 2.26 (0.89) | ||
| Complete blood count, mean (SD) | |||
| White blood cells, 109 cells/L | 7.5 (2.4) | 6.1 (1.2) | 0.047 |
| Monocytes, cells/μL | 569.5 (180.5) | 485.6 (142.6) | 0.16 |
| Neutrophils, cells/μL | 5188.0 (1969.9) | 3728.6 (1032.5) | 0.014 |
| Lymphocytes, cells/μL | 1550.0 (724.0) | 1726.7 (332.3) | 0.39 |
| Platelets, cells/μL | 187.0 (65.3) | 210.9 (34.5) | 0.21 |
| Concomitant medication, n (%) | |||
| Statin | 15 (100.0) | 15 (93.8) | 0.33 |
| Aspirin | 14 (93.3) | 15 (93.8) | 0.96 |
| ACE-I | 8 (53.3) | 8 (50.0) | 0.85 |
| ARB | 2 (13.3) | 1 (6.3) | 0.51 |
| Hydrochlorothiazide | 2 (13.3) | 1 (6.3) | 0.51 |
| Furosemide | 1 (6.7) | 1 (6.3) | 0.96 |
| Calcium-channel blocker | 3 (20.0) | 3 (18.8) | 0.93 |
| Beta-blocker | 10 (66.7) | 9 (56.3) | 0.55 |
ACE-I, angiotensin converting enzyme inhibitors; ARB, angiotensin receptor blocker; CABG, coronary artery bypass graft surgery; HDL-C, high-density lipoprotein cholesterol; hs-CRP, high-sensitivity C-reactive protein; LDL-C, low- density lipoprotein cholesterol; PCI, percutaneous coronary intervention.
P values comparing proportions were calculated with either Chi-square test or Fisher’s exact.
P values comparing continuous variables were calculated using unpaired Student’s t-test or Mann-Whitney U test.